четверг, 15 марта 2012 г.

Former foreign minister Alexander Downer, Australia's longest-serving, quits politics

Alexander Downer announced Thursday he is quitting Australian politics following a career as the country's longest-serving foreign minister and one of its highest-profile leaders of the past decade.

Downer, who was ousted from power at elections last year along with the rest of Prime Minister John Howard's conservative government, said he is in talks on taking a job as a special U.N. envoy on the conflict in Cyprus.

Downer, 56, declined to run for the leadership of his Liberal party after the coalition that had ruled since 1996 lost elections last November and has languished on the back benches of parliament while considering his future.

Floods hit central part of state

WESTON - Heavy rain overnight caused numerous creeks to overflowtoday, flooding areas of Harrison, Doddridge and Lewis counties,emergency services officials said.

Three homes in the Weston area were evacuated, said Lt. Tom McVayof the Weston Fire Department.

Standing water as deep as 3 feet covered scattered areas of LewisCounty, and all roads leading into Weston were closed, officialssaid."We've got so much rain and there's just nowhere for it to go,although it does seem the water's …

Connecting Flight; US Airways climbed out of its second bankruptcy by merging with america west. Can the new company combine its information systems?

The new US Airways, formed from the combination of low-cost carrier America West Airlines and the twice-bankrupt US Airways, officially took flight on Sept. 27. The company will announce its collective financial results Nov. 9.

But while the airline looks like one entity, its information systems remain separate and distinct. For the coming months, the company will keep two Web sites, handle reservations on two systems, and run its business applications separately.

US Airways chief information officer Joe Beery, however, is working to meld these disparate systems. Over the next two to three years, he'll try to bring the systems together into a single information …

среда, 14 марта 2012 г.

Obama calls for bipartisan cooperation on stimulus

President-elect Barack Obama is calling for bipartisan cooperation in quickly passing his economic stimulus package that Democrats say will include an unexpectedly large tax cut of up to $300 billion.

Obama says "the situation is getting worse and we have to act boldly and we have to act swiftly."

He added: "This is not a Republican problem or a …

Nigerian federation: "No choice of venue."

The Nigeria soccer federation said Monday it had no choice of venue for its exhibition match against North Korea at which a stampede left 15 people injured.

Taiwo Ogunjobi, the Nigerian federation's technical committee chairman, told website kickoff.com that "we had no choice" because "that was the only venue available to us" because "FIFA had taken control of all the stadia."

One policeman was seriously hurt Sunday during two separate fan rushes at the Makhulong Stadium outside Johannesburg.

Nigeria media officer Idah Peterside said that FIFA and World Cup organizers were not responsible, adding the match "was …

China: Textiles Generate 99% of Trade Surplus

According to Chinese customs statistics, China's textile trade for 2005 showed that exports were US$117.5 billion, up 21% from the preceding year and imports were US$17 billion, up 2%. The textile trade surplus was US$100.4 billion, up 27% from the year-ago level and exceeded US$100 billion for the first time. The greatest contributing factor is a sharp rise in exports; a …

Iran ratifies bill to pull ambassador from Britain

TEHRAN, Iran (AP) — Iran's constitutional watchdog has ratified a bill that reduces diplomatic relations with Britain following London's support of recently upgraded U.S. sanctions on Tehran.

State radio says the Guardian Council ratified the bill on Monday after parliament approved it the day before. President Mahmoud Ahmadinejad now has five days to sign the bill before Iran's foreign …

US Presbyterian church ordains first gay minister

MILWAUKEE (AP) — A Wisconsin man who left his Presbyterian ministry in California more than 20 years ago after telling his congregation that he is gay was welcomed back into the church leadership on Saturday as its first openly gay ordained minister.

In a quavering voice ripe with emotion, 56-year-old Scott Anderson told the hundreds of friends and backers who packed Covenant Presbyterian Church in Madison for his ordination ceremony that he never thought the day would come.

"To the thousands of Presbyterians who have worked and prayed for almost 40 years for this day, I give thanks," Anderson said. "And I give thanks for those who disagree with what we're doing today yet who …

Partnership Seeks to Fill Machining Talent Void

While other industries may be cutting back during the down economy, manufacturers and machine shops still face a dearth of talent to fill technical jobs. But a new partnership aims to help fill that void.

The NH Machining Association has partnered with Manchester-based Intelitek Inc., which develops and produces high-tech hybrid training systems, and Workforce Training Resources, LLC, a career training services provider based in Manchester, on a series of new programs to train entry-level precision manufacturing technicians, computer-aided machine operators and automation and robotics technicians in NH.

Intelitek is housing the new training program and providing equipment …

Chinese orchestra performs for Pope Benedict at Vatican

The China Philharmonic Orchestra performed for Pope Benedict XVI in a landmark concert Wednesday that could indicate warming relations between Beijing and the Vatican.

Benedict called it a "truly unique event" and offered a "thank you" in Chinese at the end of the hour-long concert.

He praised music as a bridge between cultures and peoples and expressed greetings "to all the people of China as they prepare for the Olympic Games." The pontiff said he wanted to reach out "to your entire people" and that he had a "special thought" for Chinese Catholics loyal to the papacy.

Benedict, a classical music …

Women on the prowl for charity

North-east women are once again being urged to sign up for amassive charity event.

The Moonlight Prowl charity walk in Fraserburgh is an after-darkwalk for women to raise cash for breast cancer research.

Last year more than 900 women, all dressed in pink, turned outfor the night-time tour of the Broch.

More than pounds100,000 has already been raised through theevent.

This summer's event is poised to become the biggest and brightestyet.

The Moonlight Prowl committee is hosting the first of a series offun registration events …

Grant Park Festival to Honor the Earth

The largest Earth Day festival since 1990 will be held in GrantPark Sunday, with rock music, speeches, environmental exhibits,vegetarian food and puppet shows.

Organizers hope to draw between 50,000 and 100,000 people.Environmental groups also have scheduled smaller Earth Day events inthe city and suburbs throughout the week.

The Grant Park festival begins at 9 a.m. with a five-milewalk-a-thon to raise money for environmental programs and communityand school activities.

Main stage events begin at 11 a.m. with a multiculturalperformance. Speeches by environmentalists and politicians willfollow, alternating with sets of live rock and jazz. California hiphop artist A.K. Black will perform his "eco-rap" at 2 p.m. Thefestival ends at 6 p.m.

The youth stage will include storytelling, theater, puppet show,magic show, rap and break-dancing. On the midway, there will beexhibits by the U.S. Environmental Protection Agency, ChicagoEnvironment Department and Earth Day Store.

The festival will be held in Arvey Field, north of Field Museum.The CTA has added extra buses that stop at or near the site. Takethe No. 1 Indiana/Hyde Park, No. 3 King Drive, No. 4 Cottage Grove,No. 6 Jeffrey Express or No. 146 Marine/Michigan Express. There alsowill be free, secured parking for bicycles.

Drive if you must, but parking is tight, and you might get dirtylooks.

The first Earth Day in 1970 helped launch the environmentalmovement. There were trash-ins, write-ins and teach-ins inCalifornia, a Dead Orange Parade in Miami and a Survival March inBoston. J. Edgar Hoover sent FBI agents to spy on a rally inWashington, D.C. In Chicago, 6,000 young people rallied at DaleyPlaza, and Mayor Richard J. Daley proposed jail sentences forpolluters.

Earth Day languished throughout most of the 1970s and 1980s butrevived in 1990, when more than 100,000 people attended a festival inLincoln Park.

Last year's Earth Day passed nearly unnoticed. Music and otherentertainment scheduled for Daley Center were canceled because theplaza was filled with emergency vehicles related to the Loop flood.

Slinky Facts

Some Slinky trivia: The Slinky business boomed during the 1950s, but in 1960, Jamesabandoned his invention, joined a religious cult and moved toBolivia, where he died in 1974. His family, including his wife,Betty, 77, continue to operate the business. More than 250 million Slinkys have been sold. The original Slinkysold for $1 retail. The same Slinky sells today for $1.99. The Slinky is made of 80 feet of wire. Slinkys come in two steelsizes, original and junior. Two plastic sizes comes in colors,including neon pink and green. Slinkys are still made on the original machines designed andengineered by James in 1945. Slinkys have been used as a component in pecan-picking machines,drapery holders, antennas, light fixtures, window decorations, gutterprotectors, pigeon repellers, birdhouse protectors, therapeuticdevices, wave-motion coils, table decorations and mail holders.

вторник, 13 марта 2012 г.

Piniella appreciates Z's mature reaction

Carlos Zambrano said he was surprised he was asked and doesn't like the idea of being a reliever. But he seems serious about trying to become the setup man Carlos Marmol was the last three seasons.

''I'm not saying that I will be Superman,'' Zambrano said. ''I'm not saying that I will be the best setup man in the business. But I will go out there and give the best that I have to be the best.

''I can be good. I can be great. It's up to me, the challenge, and it's up to what I put in my mind and how I go there.''

To manager Lou Piniella, that might have been the most encouraging aspect of the move.

''He said that he would do what's best for the team, and I'm very appreciative,'' Piniella said. ''You know, he talked about maturing. This proves it to me.''

Asked about the perception that he would be upset at the suggestion of a move to the bullpen, Zambrano said, ''Why? ... I can be the ace in the eighth inning. Why not? Mariano Rivera is the ace on that team, in that category.

''Look, man, I'm not looking for a contract here. I have three more years to put up numbers, and who knows? I may still play baseball; I may not. But this is not my last year of my contract. I just want to get a ring, just want to help this team. And if this is [how to help], I'm here for the team.''

Although Zambrano hasn't pitched as well as the other starters in the rotation, Piniella stressed his performance wasn't the reason he was asked to make the move.

''Absolutely not,'' Piniella said. ''He's throwing the ball well. Opening Day he struggled some, but after that his starts have been good.''

NOTES

Piniella said he has scheduled Ted Lilly's return from shoulder rehab for Saturday in Milwaukee, meaning Ryan Dempster, Lilly and Randy Wells would make up the Cubs' rotation for the three-game series against the Brewers.

- The fourth-inning walk Carlos Silva drew Wednesday was his first since June 20, 2002, when he pitched for Philadelphia.

- Xavier Nady, who still is working back from elbow surgery, was unavailable to start Wednesday against lefty Oliver Perez after making back-to-back starts for the first time this season Sunday and Monday. Piniella said he expects Nady to be available today against lefty Johan Santana.

- Not only was Zambrano willing to go to the bullpen, but Piniella said he also offered to play in the outfield if needed.

''We can double-switch. He'll be the double switch,'' Piniella said.

Comment at suntimes.com.

TONIGHT'S GAME 6:10, Ch. 26, 720-AM

Cubs (6-9) at Mets (6-9)

Tom Gorzelanny

0-1, 1.93 ERA

'09 vs. Mets:

1-0, 0.00 (4 G, 0 GS)

Career vs. Mets:

2-2, 5.68 (4 GS, 8 G)

Mets vs. Gorzelanny

David Wright: 2-for-7, 2 2B

Jose Reyes: 2-for-8, 2 RBI, 2 BB

Jeff Francoeur: 1-for-9, RBI

Luis Castillo: 0-for-3

Fernando Tatis and Angel Pagan:

0-for-1

Johan Santana

1-1, 3.00 ERA

'09 vs. Cubs:

Did not face

Career vs. Cubs:

2-0, 1.71 (2 GS, 5 G)

Cubs vs. Santana

Kosuke Fukudome: 2-for-3, 2B, RBI

Derrek Lee: 2-for-6, 2B, HR

Xavier Nady: 1-for-6

Alfonso Soriano: 0-for-10, 2 BB

Marlon Byrd: 0-for-3, 3 K

Aramis Ramirez: 0-for-4, 2 K

Color Photo: Johan Santana Color Photo: Tom Gorzelanny

Putin denies tabloid report that plans to marry former champion gymnast

Russian President Vladimir Putin on Friday denied a tabloid report that he had divorced his wife and intended to marry a champion gymnast less than half his age.

"There is not a single word of truth" to the report carried by a Moscow tabloid, Putin said at a news conference in Sardinia with incoming Italian Premier Silvio Berlusconi.

But he did not stop there. Putin, who has seemed to enjoy playing up the image of a ladies' man and who clearly relished the question from the Kremlin pool reporter, went on to say that he likes all Russian women.

"In other publications of the same type, the names of other successful, beautiful young women from Russia are mentioned," he said. "I think it won't be unexpected if I say that I like them all _ just as I like all Russian women."

He called Russian women "the most talented and beautiful" in the world.

"If anyone can compete, it may be only Italian women," Putin said, in a nod to his Italian hosts.

The tabloid Moskovsky Korrespondent reported Saturday that Putin, 55, divorced his wife, Lyudmila, two months ago and planned to marry Alina Kabayeva, 24, a former champion rhythmic gymnast. His wife did not accompany him to Sardinia.

Kabayeva, who won a gold medal at the 2004 Summer Games, is now a member of the lower house of Russia's parliament from the pro-Kremlin party.

Her spokeswoman has refused to comment on the report, which said the information came from the close friend of the head of a company bidding to hold the wedding in St. Petersburg on June 15.

Putin, using the earthy language that has become his trademark, scolded the press for intruding on his private life.

"I have always had a negative opinion of those who, with their snotty noses and their erotic fantasies, meddle in other people's lives," he said.

The tabloid report, largely ignored in the Russian press, has had wide play in European newspapers.

____

Associated Press Writer Lynn Berry contributed to this report from Moscow.

Pozzato wins 12th stage of the Giro

Filippo Pozzato became the first Italian to win a stage at the 2010 Giro d'Italia after taking the 12th stage in a sprint finish Thursday.

The Italian national champion squeezed across the line ahead of French duo Thomas Voeckler in second and Jerome Pineau in third.

"I knew I had to attack and I trusted my legs," Pozzato said. "It is a dream to be the first Italian to win a stage at the Giro this year and of course I'm happy. I hope I'm not the only Italian to win a stage and I expect my fellow Italians to start winning stages now."

Pozzato finished the 206-kilometers (128-mile) stage from Citta Sant'Angelo to Porto Recanati in 5 hours, 15 minutes, 50 seconds.

Rick Flens made the first attack, breaking from the lead pack after 9 kilometers. Yuriy Krivstov and Olivier Kaisen then joined him at the front after 18K and the three kept their distance from the chasing group until being caught in the closing stages.

Michele Scarponi led Alexandre Vinokourov over the final kilometer, before Pozzato broke out of a group of six riders to take the win.

Richie Porte of Australia kept the pink jersey as overall leader, remaining 1 minute, 42 seconds ahead of David Arroyo Duran in second.

"It was great today, it was a beautiful day," Porte said. "Riding in the pink jersey is tough full stop, but I have a fantastic team and we rode well today."

Pat White not in 'concussion state'

MORGANTOWN - West Virginia quarterback Pat White was knocked outof a second consecutive game Saturday, but this time it was a hit tothe head against Rutgers and not an aggravation of the left thumbinjury that sidelined him against Marshall.

"He's not in any kind of a concussion state at all," WVU CoachBill Stewart said. "If everything progresses as we think, he'll bein the lineup Saturday. He does not have a concussion. He's OK.(Taking him out of the game) was a precautionary measure."

Stewart said he was in regular contact with White's familySaturday night, but there was no cause for alarm. White was woozyafter leaving the game, but he suffered no memory loss, nausea orany other symptoms of a concussion.

White left the game after running for 10 yards on a third-and-nine in the third quarter. He tried to slide at Rutgers' 4-yard linebut was hit by Ryan D'Imperio. White went to the locker room andreturned a while later but didn't get back in the game.

White was 12-for-17 for 137 yards and two touchdowns and ran for59 yards on 11 carries before getting hurt.

An 18-yard run in the first quarter moved White into second placeon the NCAA's all-time career quarterback rushing list. He now has44 career touchdown passes, behind only Rasheed Marshall (45) andMarc Bulger (59) on WVU's all-time list. White jumped Oliver Luckand Chad Johnston with his second-quarter touchdown pass to JockSanders.

* n n

REED WILLIAMS didn't play Saturday and won't play the rest of theseason.

Stewart said the senior middle linebacker from Moorefield willtake a medical redshirt.

"That's my call," Stewart said. "I'm not going to play anybodywho can't protect himself. I'll never play anybody that I don'tthink is in good enough condition or good enough physical shape toprotect himself on the field or can't play full-speed. If you can'tplay full-speed, you can't play the game. It's a fast, fast violentgame."

WVU's leading tackler last season and the most valuable defensiveplayer in the Fiesta Bowl, Williams missed the first two games thisseason and played in the past two. He had 17 tackles - No. 6 on theteam - and an interception and made the Big East's weekly honor rolllast week.

However, Stewart said early last week Williams was "questionable"and "hurting."

"If you guys had a chance to see him after a game, you'd knowexactly what he was going through," said one of Williams' roommates,kicker/punter Pat McAfee. "The kid is in tremendous pain after eachgame. He's such a big force for our defense and such a good leader.It sucks. We're going to miss him, but he made the right decision,for sure. I told him he had to be comfortable with his decision.Obviously, he's a competitor and wants to play, but I think he madethe right decision. He was bummed out for a few days, but I told himhe's got to get past it, and he's doing better."

Williams didn't meet with the media after the game.

WVU initially believed it needed to make a final decision about amedical redshirt before the Rutgers game, but it discovered later inthe week Williams could have played against Rutgers and again thisweekend against Syracuse.

The redshirt rule says a player can play in 30 percent of thegames in the first half of the season. In Williams' case, 30 percentwould have been four games.

McAfee said Williams decided to take the redshirt before he foundout about the exact interpretation of the rule.

"After he went through the emotional heartache and decided toredshirt, it was like, 'Hey, you could play two more games,'" McAfeesaid. "But he'd already been through all of it."

Sophomore Anthony Leonard made his second career start at middlelinebacker and had a team-high nine tackles. Senior outsidelinebacker Mortty Ivy played in the middle on many passing downs andhas started in the middle once this season.

* n n

McAFEE'S FIRST-QUARTER extra point gave him 324 career points andmoved him into first place on the school's all-time kicker scoringlist.

He entered the game tied with Paul Woodside (1981-84) and hemight have left the game with no memento of the occasion.

After the kick, an official gave the ball to McAfee, only forMcAfee to give it back. The senior from Plum, Pa., didn't realizewhat happened until after the game.

"Oh, my God, you just explained that to me," McAfee said. "I wasso confused. He asked me if I wanted the ball. I thought he meantfor the kickoff. Wow, I'm so slow. He had to have given it tosomeone (from WVU). He must have looked at me like an idiot. Wow, Ididn't know that. And I don't know where the hell it is."

McAfee had two more extra points and a field goal against Rutgersand now has 329 career points, one shy of running back SteveSlaton's school record.

"It's more a compliment to the offenses I've been behind," McAfeesaid.

McAfee ranks No. 6 in all-time Big East scoring and is No. 3among kickers. He's in second place on the Big East's career extrapoints list with 188 in 190 attempts. He needs three to passVirginia Tech's Carter Warley.

* n n

FRESHMAN TIGHT end Tyler Urban didn't run a pass route againstColorado and ran one last week against Marshall.

No wonder he was so open on his first-quarter touchdown againstRutgers.

"I think this one caught them completely off guard," he said. "Icame off and started blocking and went out and there was no one outthere."

On second-and-two at Rutgers' 25, Urban was on the left end ofthe line of scrimmage and White was in the I-formation in front offullback Will Johnson and running back Noel Devine. Receiver WesLyons came in motion from left to right when the ball was snappedand acted as a decoy.

White faked to Devine and rolled left. A safety stepped forwardto cover receiver Alric Arnett coming across the field and alinebacker followed Devine toward the left sideline.

Urban ran uncovered into the end zone, where he caught his firstcareer pass.

"It seemed like it was in the air forever," he said.

Mike Villagrana, who now is a WVU graduate assistant, was thelast tight end to catch a touchdown. He did so 37 games ago againstVirginia Tech in 2005. It was also Villagrana's first and onlycareer catch.

"You trying to say something?" Urban said.

COOL

Miss "Mr. Ed"? He, Herman Munster and all the other video iconsof the past are residing in Nostalgic TVLand Internet Theme Park.This funny site is hosted by the Monochrome Man, who takes viewersthrough TV history.

Morton Grove resident Guy Spiro maintains the Lightworks site,devoted to astrology and New Age issues. Back copies of Spiro's TheMonthly Aspectarian magazine are on line. One of the mostinteresting features is the Astro-Weather prediction, which iscompletely unlike traditional sun-sign horoscopes. The site also hassome lovely angel artwork.

Groundhogs say spring is on the way

Thousands of winter-weary people who waited through a rainy nightwere rewarded this morning: Groundhog Punxsutawney Phil didn't seehis shadow.

That means, according to legend, that spring is just around thecorner.

A cheer went up as members of the local Groundhog Day club madethe announcement, shortly after dawn. If Phil had seen his shadow,it would have meant six more weeks of winter.Many around the country eagerly await Phil's annual Groundhog Daypredictions.But West Virginians know Concord Charlie is the utmost expert andauthority on Groundhog Day, said Concord College spokesman Tom Bone.And he agrees with Phil - winter is on the way out. French CreekFreddy, who maintains a residence at the West Virginia WildlifeCenter, also failed to see his shadow, said biologist Bill Vanscoy.Van scoy said overcast skies in Upshur County probably played apart.Concord Charlie, a furry fantasy at Concord College, allegedlylives in a burrow on the north end of the Athens campus nearAndersonField.Each year, West Virginians await the moment when Jerry Beasley,president of the college, reports on his conversations with thereputable, well-respected rodent."Concord Charlie did not see his shadow, in agreement with somegroundhog up in Pennsylvania," Bone said.Each year, the president of Concord College goes in search ofCharlie and has a long, philosophical conversation with him, Bonesaid. This has been going on for 22 years."People question the lifespan of a groundhog," Bone said. "But ifthe president of the college says he spoke to the groundhog, I'm notgoing to argue."It was the same cheery news - if you believe in such things - inLilburn, Ga., where Georgia's groundhog forecaster, Gen. BeauregardLee, also failed to see his shadow. Cloudy skies chased shadows awaywhen the 9-year-old prognosticator came out of his small mansion at7:34 a.m.The Groundhog Day tradition is rooted in a German superstitionthat if an animal casts a shadow on Feb. 2 - the Christian holidayofCandlemas - bad weather is coming. But in the 110 years since Germanfarmers began the festival in Punxsutawney, the morning of Feb. 2hasevolved into an elaborate show of hoodwinkery.In years past, members of the club voted the night before whetheror not Phil would see his shadow, rain or shine. Despite overcastskies last year, the club announced the shadow appeared. They setoff fireworks to simulate a sunrise.This year, club members insisted, they did not decide what Phil'sdecision would be until they actually approached his burrow.

Does a recession affect your CD sales?

[Graph Not Transcribed]

In a word, NO. Just because the media is projecting that the country's economy is slow or in a recession doesn't mean your CD sales are affected. People don't buy less of your CDs because the media says people are buying less of everything else. Just like if the economy was in a "boom" or growth period. Does that mean suddenly people will be buying thousands of your CDs?

Unfortunately people in our country are easily persuaded by the media. If they say less of a certain product is being sold, people fear the worse. The problem is that businesses often forget or don't recognize that the reasons they are not selling more is not based on the media's perception of the economy, but the fact that they are no longer doing business effectively. i.e. Their product costs too much, it's too old, people already have one or more of them, etc. Businesses slow down in sales because they forget to promote their product! Especially the value of it!

Take your music for example. When was the last time you sent a newsletter to your fans thanking them for coming to your past shows, buying your CDs and giving them a real update as to what is happening with you and your music? When is the last time you sent an update to the press about how great things are going? New fans, more attendance at shows, more CD sales than before, etc. Or did you merely send an e-mail announcement to them as well as your mailing list saying once again you are playing the same songs at the same bar?

Recessions are like anything else in business: a state of mind. If you want to sell more CDs or get more exposure for your music, start promoting it differently. Play a show for a change (at a new venue) that features songs focused on a central theme. Promote the show to new fans that will be interested in that particular topic.

Instead of doing what you have always done to get where you are right now in your career, challenge yourself to change! Think outside the box you created for yourself.

Let me leave you with this thought. Recently a business friend of mine introduced me to someone new in the entertainment field at a dinner party. After the introduction I asked him how business was. For 15 minutes he talked about how he was selling less product, the economy was bad, he blamed everything on George Bush, there was a war on, some people in the world didn't like him, even though others loved him, he got stuck in traffic, etc. Whatever he could think of greatly affected his business and how much product his company sold. After his dismal projection, he stopped and said to me, "How is your business doing?" I simply said, "Great." Dumbfounded by this he said, "What do you mean?"

I said, "Well there's a recession going on. Since people are supposedly buying less they have more money to spend with me. Even though I have met George Bush and have talked with him a few times in the past, he hasn't done anything to affect my business. The war won't affect how much of a product I sell and there will always be people in the world that don't like what I am doing while others love me. Those who don't like me don't understand what I'm doing or they can't hear what I'm saying. Finally, I got stuck in traffic too. It gave me extra time to think of new ways to promote my business."

"You see the media says there's a recession going on. I just decided not to be part of it."

Tim Sweeney & Associates is a 19-year-old company bent on building and fuelling the careers of new artists. Visit him online at www.tsamusic.com.

Heirloom vegetable seeds find modern-day audience

I swore I wouldn't order another seed this spring, but that wasbefore I heard Jan Blum give a little talk at the New York BotanicalGarden. Blum, a gardener from Boise, Idaho, got interested inheirloom vegetables years ago when an 84-year-old friend handed hersome seeds - of large royal kidney beans given to him as a weddingpresent back in the 1920s - and suggested she plant them.

Now her 6-year-old company, Seeds Blum, offers a collection ofheirloom vegetable, herb and flower seeds (including the royal kidneybean) that makes the Early Girl tomato and the Boy O' Boy marigoldlook sort of ho-hum by comparison.

Blum flashed a series of gorgeous red tomatoes on the slidescreen: Super Italian Paste, a 4-by-6-incher, and New Zealand Pear,the size and shape of a Bartlett pear - both of which are supposed tomake a tangy sauce once thought to have passed away with ourgreat-great-grandmothers.

But praise be, people have gone back to cultivating theirancestors' seeds. Blum's Currant tomato, for instance, a succulentcherry tomato about the size of a pea, harks as far back as theAztecs of Peru.

"Commercial varieties have been bred for certain traits thataren't important to the backyard gardener - like shipping longdistances and ripening all at once," Blum told her salivatingaudience. "But these heirloom varieties have been saved because theyare the best for the home gardener."

Why? Because of flavor, of course, or crunchiness or juiciness,or an exquisite color or fragrance that's like no other. (Imagine amarigold that looks like an impatiens and smells like a lemon.)

Blum tempted us with a picture of an old-fashioned jar ofGrandma's butter beans. These, she said, taste as if they've beenslathered in butter. But fitness freaks can relax; the flavor's allin the bean. The only problem is, the seeds aren't available untilnext year (so don't go ringing Blum's phone off the hook).

The company puts all its "new" old varieties through variousgermination and taste and texture tests before passing them on to us.But you, too, can become part of the research in this company - bygrowing such seeds in a trial garden or sending the company your ownfamily favorites.

"For a while we were losing these varieties because the oldergardeners were dying off, but now younger people are starting to saveseeds," said Blum.

Blum's collection of eggplants and peppers almost elicited sobsfrom the audience - because, rationally speaking, it's too late tostart these from seed for this summer. But as each slide passedbefore our eyes, the urge to try them, even at this late date, wasalmost irresistible.

Blum showed us Snake Eyes, a baby eggplant variety that grows ingrapelike clusters and is cooked in the skin and then mashed. Sheshowed us Baby White Tiger Stripe, whose tasty seeds add crunch to asummer stir-fry. Her collection of peppers included themahogany-colored Sweet Chocolate and the deep orange Tequila Sunrise.

The potato collection - heirloom varieties such as the100-year-old yellow Bintje, a deep pink Ruby Crescent and All Blue -not only can turn a plate of sliced new potatoes into a rainbow ofcolors, but Blum promised their earthy pungent flavor will makebattling the potato bug well worth the struggle.

For those brave and patient enough to grow melons, Blum'sfavorite this year is Moon and Stars: a very sweet, brightred-fleshed variety, whose dark green skin is actually splashed withyellow stars and a large golden moon.

Certainly Blum is not the first to sell heirloom seeds; it'sjust that her catalog reawakens something the slicker companies seemto have lost - a sense of community among gardeners that comes fromswapping seeds and family secrets. Her notes and comments have afolksy, yet disciplined air that walks that delicate line betweendown-home sappiness and brittle-dry science.

For a catalog, send $2 to Seeds Blum, Idaho City Stage, Boise,Idaho 83706.

понедельник, 12 марта 2012 г.

Report: 3 Swiss to avoid trial in nuclear case

BERN, Switzerland (AP) — Swiss prosecutors will opt to avoid a public trial for three Swiss men suspected of giving nuclear weapons technology and supplies to a rogue network in Pakistan, a newspaper reported Sunday.

The case is politically sensitive for Switzerland and the United States because of alleged national security implications, the men's alleged CIA ties, and repeated instances of evidence being destroyed. It involves charges of violating Swiss nonproliferation laws.

The Federal Prosecutors Office in Bern was quoted as saying it plans to use a shortened procedure to require a penalty but no trial if the nation's top criminal court doesn't object and the men plead guilty, the Zurich weekly newspaper SonntagsZeitung reported.

Bern prosecutors' office did not immediately respond to an Associated Press request for comment.

Urs Tinner, his brother Marco and their father Friedrich have been under investigation by Swiss authorities for almost a decade for supplying equipment and technical know-how to an international smuggling ring led by Pakistani scientist Abdul Qadeer Khan.

Urs Tinner was released in December 2008 after almost five years in investigative detention without being charged.

As the creator of Pakistan's atomic bomb, Khan sold the centrifuges for secret nuclear weapons programs in countries that included Libya and Iran before his operation was disrupted in 2003.

A spokeswoman for the federal prosecutors, Walburga Bur, has previously told AP that a shortened procedure was possible under which the Swiss engineers admit the basic charges against them but face no more than five years imprisonment. Normally, anyone who breaks Swiss laws banning the export of nuclear material faces up to 10 years imprisonment.

Urs Tinner, who like his brother and father has been released on bail pending charges, claimed in an 2009 interview with Swiss TV station SF1 that he had worked with U.S. intelligence. He said he had tipped off the CIA about a delivery of centrifuge parts meant for Libya's nuclear weapons program.

The CIA has declined to comment on the case.

The shipment was seized at the Italian port of Taranto in 2003, which forced Libya to admit and eventually renounce its efforts to acquire nuclear weapons, and helped expose Khan's smuggling ring.

The case against the Tinners sparked a political outcry in Switzerland after it was revealed that the Swiss government repeatedly ordered evidence destroyed, allegedly under pressure from senior U.S. officials.

The Swiss government cited national security concerns, but a parliamentary investigation found there had been no immediate danger to Switzerland's security.

A Swiss investigating magistrate, Andreas Mueller, who oversaw the last three years of a six-year federal probe against the Tinners, recommended last December that the government bring charges against the three men.

Mueller said his recommendation, contained in a confidential report to federal prosecutors, was based on an exhaustive probe. He said the Tinners had worked for the CIA since June 2003 and did not deny also working for the Khan network.

3 dead, 70 others rescued in Philippine ferry fire

MANILA, Philippines (AP) — An inter-island ferry with at least 75 people caught fire then sank amid stormy weather in the central Philippines on Sunday, leaving 3 people dead, one missing while the rest were rescued, officials said.

The steel-hulled M/V Island Fastcraft 1 was cruising toward Cebu province when it caught fire during a downpour, prompting several passengers to jump into the churning waters. Three of them drowned.

Henry Dungod said he, his wife and two young daughters were watching television with other passengers in a cabin when smoke suddenly wafted from below the ferry, sparking a panic. He and his wife grabbed life jackets and then jumped to the sea, each holding one daughter.

"It's scary, especially when something like this happens and you're with your family," Dungod told The Associated Press by telephone, adding he and his loved ones were plucked from the waters by a passing ship after nearly an hour.

Most of the passengers were rescued by a passing ship, coast guard officer Fidel Hibaya said.

Coast guard chief Admiral Ramon Liwag said one passenger was reported missing.

It was not immediately clear what sparked the blaze, but there was a report of an electrical problem in the engine room before the fire. An investigation was under way, Liwag said.

The captain apparently ordered passengers and crew to abandon the ship when the fire began to spread, said Hibaya, commander of the coast guard detachment in Tubigon town in Bohol Province where the ferry originated.

The dead included the chief mate and two passengers, the coast guard said.

Liwag said his personnel alerted ships in the area to help in the rescue, preventing a larger number of casualties.

Sea accidents are common in the Philippine archipelago because of frequent storms, badly maintained boats and weak enforcement of safety regulations.

In December 1987, the ferry Dona Paz sank after colliding with a fuel tanker in the Philippines, killing more than 4,341 people in the world's worst peacetime maritime disaster.

Ex-Diplomat Faults Policy on N. Korea

WASHINGTON - A former State Department official who maintains contact with North Korea said Thursday U.S. dealings with that country have been hampered by missteps and lack of a coherent policy.

"You can't get anywhere without a clear roadmap, and we don't have one," said Kenneth Quinones, who served as State Department liaison with North Korea's U.N. mission between 2004 and 2006.

He said a promising efforts last year to resume six-party nuclear disarmament talks fell by the wayside when President Bush referred to North Korean Chairman Kim Jong Il as a "tyrant."

Quinones, who spoke at the U.S.-Korea Institute, said the North Koreans told U.S. officials, "We're not coming back until the president stops the criticism."

Weeks later, he said, there was fresh progress toward a new round, but Defense Secretary Donald Rumsfeld soured the atmosphere when he announced stealth fighter planes were being sent to South Korea.

Talks were finally resumed in Beijing in September 2005, and the session ended with a breakthrough communique that included broad agreement on a number of issues, including a North Korean commitment to dismantle its nuclear weapons.

But the good feelings dissipated within 48 hours, Quinones said, when a dispute erupted over whether North Korea should receive light water reactors before carrying out nuclear disarmament.

North Korea agreed recently to return to the six-party talks after a boycott of almost a year. Since the last round, the North has tested missiles and a nuclear device.

As a result, Quinones said, "the price for a diplomatic resolution will be far higher than it would have been last year." The next round could start before the end of the year.

Quinones said that North Korea is eager to revive the 1994 Agreed Framework under which it was to receive two light water nuclear reactors in return for the freezing of nuclear facilities at Yongbyon.

That agreement lapsed in late 2002, one element in a steady deterioration in relations with the United States. Work on the reactors, financed by Japan and South Korea, has been suspended for several years.

Quinones once served as North Korea desk officer at the State Department. He retired from the diplomatic corps in 1996 but was recalled to duty in 2004 for the intermediary role with the North Korean U.N. mission.

He said mistrust has permeated the U.S.-North Korean relationship.

"The North Koreans don't want to negotiate with a government they do not comprehend," he said. "They found that the rules constantly changed."

Mistrust "can be devastating to diplomacy," he said.

To the Brink: Indian Decision-Making and the 2001-2002 Standoff

Reports of Note

This report examines the 2001-2002 standoff between India and Pakistan that followed a December 2001 attack on the Indian parliament by terrorists operating out of Pakistan.The 10-month confrontation occurred less than four years after India's and Pakistan's 1998 nuclear weapon tests and was the largest military mobilization since World War II. Stolar explores the Indian decision-making process in an attempt to understand how and why India's leaders pursued the strategy they did. His analysis is based on interviews with two former members of India's Cabinet Committee on Security, as well as other senior Indian national security officials.

Stolar ends his report by drawing four conclusions. First, there are limits to traditional nuclear deterrence theory. Second, a limited war between nuclear states entails substantial risks of escalation, and leaders must factor these risks before carrying out a limited military action. Third, national leaders must convey information to a myriad of domestic and international audiences during a crisis, a task both essential and extraordinarily challenging. Finally, the study illustrates the challenges of interagency coordination during crises and the importance of overcoming such challenges.

[Author Affiliation]

By Alex Stolar, The Henry L. Stimson Center, February 2008.

Sheshunoff Managing Bank Investment Portfolios

Sheshunoff Managing Bank Investment Portfolios, by Leonard Matz, Sheshunoff Information Services Inc., Austin, Tex., $325. This manual was written to give bankers guidance and techniques they need to make the most of opportunities in the bank investment portfolio to help meet bankwide risk and profit goals. This investment portfolio guide, according to the publisher, is the only one just for bankers that focuses on how to manage the portfolio, rather than individual instruments. The author uses clear, practical examples and strategies to show bankers how to improve an investment portfolio to achieve acceptable levels of interest rate and credit risk and meet regulatory risk management guidelines. The focus is on helping bankers develop and implement a comprehensive portfolio management strategy that meets these criteria and maximizes the portfolio's profit potential. The guidance is specific and hands-on.

Stock Futures Headed to Flat Open

NEW YORK - Wall Street headed for a flat open Monday before a report expected to show home resales slipped in May, data that would suggest that the Federal Reserve won't have to raise interest rates.

Investors expect the National Association of Realtors to report existing home sales totaled 5.97 million in May, down from April's level 5.99 million. If May's results match projections, they would reflect a drop of 0.3 percent from April, and 10.6 percent from the same month last year. The report is released at 10 a.m. EDT.

On Tuesday, the Conference Board releases its June consumer confidence index and the Commerce Department's on new home sales for May. The latest batch of economic indicators comes before the Federal Reserve meets on Wednesday to discuss interest rates. Central bankers are widely expected to keep the benchmark rate stead at 5.25 percent, while Wall Street will be braced for any clues about future moves.

Investors sent stocks lower Friday as concerns grew that major U.S. financial institutions will be hurt by losses from mortgage-backed securities. Bear Stearns Cos. recently announced it would help to rescue two of its hedge funds that are near collapse, and caused concern others might be next.

Last week, the Dow Jones industrial average lost 2.1 percent, while the Standard & Poor's 500 fell 2 percent and Nasdaq composite index lost 1.4 percent.

Dow futures expiring in September rose 9 points, or 0.07 percent, to 13,515, before Monday's open while S&P 500 futures rose 0.30, or 0.02 percent, to 1,520.80. Nasdaq 100 index futures rose 5.00, or 0.26 percent, to 1,953.75.

There was little in the way of corporate news Monday. General Motors Corp. will likely move higher after Goldman Sachs upgraded the automaker to a "buy" from "neutral." Goldman said there was little downside for the company's stock, and that it could rise sharply depending on how discussions with labor unions end.

Rupert Murdoch was said to be near a pact to guarantee editorial independence of the Wall Street Journal if News Corp. acquires Dow Jones & Co., according to newspaper reports on Sunday.

Drugstore operator Walgreen Co. reported fiscal third-quarter profit rose nearly 20 percent, helped by sales growth at established stores and an increase in prescription sales.

Oil futures dropped 68 cents to $68.42 in premarket trading on the New York Mercantile Exchange. A U.S. Senate subcommittee wants strong energy market oversight after Amaranth Advisors lost $6 billion on bad bets in the U.S. natural-gas market.

Overseas, Japan's Nikkei stock average fell 0.56 percent, while the sometimes-volatile Shanghai Composite Exchange fell 3.7 percent. Britain's FTSE 100 fell 0.24 percent, Germany's DAX index fell 1.03 percent, and France's CAC-40 fell 0.78.

---

On the Net:

New York Stock Exchange: http://www.nyse.com

Nasdaq Stock Market: http://www.nasdaq.com

среда, 7 марта 2012 г.

TICKET LINE

Although John Panozzo has passed away, veteran Chicago rockers Styxare soldiering on, with their first tour since the death of theirdrummer and co-founder. The final leg of their Paradise Theatre tourwill bring them to the Rosemont Horizon for a show at 7:30 p.m. Sept.21.

Speaking of carrying on, Kansas, the wayward sons who wrote thebook - er, song - on the subject, will join Styx for an evening ofhits from the late '70s and early '80s. Tickets are $24.75, $37.25and go on sale 10 a.m. Saturday.

Styx had broken up in 1984, but reunited for the current tour.Panozzo died in July of gastrointestinal bleeding.

The Horizon is located at 6920 N. Mannheim, …

Al-Qaida's American-born member lashes out at US in first message of 2008

Al-Qaida's American-born member Adam Gadahn lashed out at the United States and its allies in new video posted Sunday, marking the terror network's first message of 2008.

Gadahn, who was born in California, said al-Qaida felt the need to release a statement to ordinary Americans after Washington's "defeat" in Iraq and Afghanistan and failed attempts by U.S. President George W. Bush and other diplomats to bring peace to the Middle East.

"We felt it necessary to address the American people and explain to them some of the facts about these critical and fast-moving events," said Gadahn, who wore a white and red headscarf.

вторник, 6 марта 2012 г.

Group wants cascading style sheets in IE 5.0.(Microsoft Internet Explorer 5.0 Web browser)(Product Development)

IDG News Service

The Web Standards Project (WSP) is urging Microsoft to make its upcoming Internet Explorer 5.0 Web browser fully compliant with the Cascading Style Sheets (CSS) standard.

WSP is an international coalition of Web developers and Web experts who are encouraging browser makers to support CSS Level 1 (CSS-1), the Document Object Model (DOM) and extensible markup language (XML) in their browsers before adding new features.

While Microsoft has made gains in making its IE 5.0 Web browser, which is now in beta testing, CSS-1 compliant, a number of fairly major problems prevent the layout of Web pages from working properly, said George Olsen, …

Group wants cascading style sheets in IE 5.0.(Microsoft Internet Explorer 5.0 Web browser)(Product Development)

IDG News Service

The Web Standards Project (WSP) is urging Microsoft to make its upcoming Internet Explorer 5.0 Web browser fully compliant with the Cascading Style Sheets (CSS) standard.

WSP is an international coalition of Web developers and Web experts who are encouraging browser makers to support CSS Level 1 (CSS-1), the Document Object Model (DOM) and extensible markup language (XML) in their browsers before adding new features.

While Microsoft has made gains in making its IE 5.0 Web browser, which is now in beta testing, CSS-1 compliant, a number of fairly major problems prevent the layout of Web pages from working properly, said George Olsen, …

понедельник, 5 марта 2012 г.

Foreword

For over ten years, the Manitoba Centre for Health Policy (MCHP) has been providing accurate and timely information to health care decision-makers, analysts and providers, so that policies, programs and services intended to improve the health of Manitobans can be efficaciously designed and implemented. MCHP delivers leading-edge research in the areas of health service utilization, health and illness patterns in the population, and the factors that affect health, all of which are critical to informing the health policy process.

Over the past several years, there has been a growing interest in child health and wellbeing as health policy-makers and researchers have turned their …

People and organisations involved in the case.

Who and what is involved in the inquiry:

Personalities

Commissioner: attorney Jan Reitz

Andre Kriel - Southern African Clothing and Textile Workers' Union (Sactwu) general secretary

Wayne van der Rheede - suspended Sactwu deputy general secretary

Enoch Godongwana - part-owner of Canyon Springs who later became Deputy Minister of Economic Development

Thandiwe Godongwana - Enoch's wife and part-owner of Canyon Springs

Mohan Patelo - Cape Town businessman and part-owner of Canyon Springs

Richard Kawie - former Sactwu consultant

Sam Buthelezi - investment manager, director and owner of the Trilinear …

RADIO RATINGS FIGURES SKEWED BY CHANGES.(Weekend)

Byline: Will Hughes Staff writer

The final quarter of 1988 may set a record for the most format, call letter and on-air personality changes in the history of local radio.

Some local broadcasters say the changes may skew fall ratings.

Fall ratings from Birch Scarborough Research, released today,

show some surprises and some consistency.

WPYX-FM (106.5) retains the top position in listeners, 12 years and older, with a 13.9 rating. WFLY-FM (92.5) is second with a 10.1 and WGY- AM (810) is third with an 8.8.

A surprisingly strong 6.9 - up from a 5.3 last fall - propelled WTRY-AM (980) into fourth place, the oldies station's …

GRASSLAND TO GET AWARD.(Business)

Grassland Equipment & Irrigation Corp., a wholesale outdoor power equipment distributor, will receive the 1989 Small Business of the Year Award from the Albany-Colonie Regional Chamber of Commerce tonight.

Horst Pogge, Grassland owner and president, started the business in 1962.

A distributor of Toro equipment in eastern New York and Vermont, the firm also specializes in selling turf maintenance equipment, golf course supplies, fertilizers and chemicals.

Since he started in the business, Pogge said the greatest strides in the industry have been made in underground irrigation, which has become his …

Reports: Rio Police Kill 9 Suspects

Heavily armed police cracking down on crime ahead of carnival celebrations engaged in shootouts with criminals in two slums Wednesday, reportedly killing nine suspects.

A police spokeswoman confirmed that the operation was under way in the Jacarezinho and Mangueira slums, but said authorities would not comment on deaths or injuries until it was finished. She would not give her name in keeping with department policy.

Rio de Janeiro's O Globo and O Dia newspapers reported on their Web sites that nine suspects were killed, quoting a police inspector at the scene. O Globo said five suspects were injured and six were taken into custody.

Officers …

McEnroe toppled in Tokyo; Lendl, Edberg advance

Jim Courier dismissed John McEnroe 6-2, 6-2 Friday to join StefanEdberg, Ivan Lendl and Michael Chang in the semifinals of the JapanOpen in Tokyo.

Courier hit 73 percent of his first serves. Rapidly firing bothshots and serves, he broke the second and eighth games of the firstset.

"I served well and returned well," Courier said. "I alwayswent ahead of him and that was good for me. I played better thanusual."

McEnroe said he was unable to put pressure on Courier. "I couldnot win a point when I wanted to," he said.

Chang advanced by defeating Pat Cash 6-4, 6-1. Defendingchampion and top seed Stefan Edberg advanced by outlasting MichaelStich …

воскресенье, 4 марта 2012 г.

Research on Carcinomas Reported by Scientists at Oita University.(Report)

"Purpose The aims of this study were to compare the usefulness and reliability of integrated whole-body positron emission tomography/computed tomography (PET/CT) using F-18-fluorodeoxyglucose (FDG) with those of contrast-enhanced multidetector CT during regular follow-up in patients after initial treatment of ovarian cancer, to assess the impact of FDG-PET/CT on the confirmation of recurrence, restaging, and clinical management of patients, and to determine the incremental information provided by PET/CT. Methods A retrospective review was performed on 19 ovarian cancer patients who underwent a total of 30 FDG-PET/CT and contrast-enhanced multidetector CT scans," scientists writing in …

The surface protein Shr of Streptococcus pyogenes binds heme and transfers it to the streptococcal heme-binding protein Shp.(Research article)

Authors: Hui Zhu [1]; Mengyao Liu [1]; Benfang Lei (corresponding author) [1]

Background

Specific ATP-binding cassette (ABC) type transporters are involved in acquisition of essential iron in various forms in bacterial pathogens. The substrate-binding component of the ABC transporters specifically binds free Fe

3+ , ferric siderophore complex, or heme, which is transported across the cytoplasmic membrane by the permease component using the energy from the hydrolysis of ATP catalyzed by the ATPase component [1]. The human pathogen Streptococcus pyogenes produces three ABC transporters, FtsABCD [2], HtsABC or SiaABC [3, 4], and MtsABC [5], which acquire ferric ferrichrome, heme, and Fe3+ and Mn2+ , respectively. Expression of htsABC and mtsABC are negatively regulated by the same metalloregulator MtsR in response to levels of Fe only and Fe or Mn, respectively [6, 7].

Heme is abundant in mammalian hosts and a preferred iron source for bacterial pathogens [8, 9, 10, 11]. Besides heme-specific ABC transporters, cell surface heme-binding proteins are required for heme acquisition in Gram-positive pathogens. These proteins have been identified in

S. pyogenes [12], Staphylococcus aureus [13], and Streptococcus equi [14]. Heme is usually bound to host proteins at extremely high affinities [15, 16]. Furthermore, Gram-positive bacteria have thick cell walls, and heme-specific ABC transporters are most likely buried in the cell wall. Thus, heme acquisition machinery in Gram-positive bacteria may have to have evolved mechanisms to overcome these obstacles in heme acquisition, i.e. inability of host hemoproteins to reach the ABC transporters and the extremely high affinity of host proteins for heme. The cell surface heme-binding proteins are believed to have evolved to overcome these obstacles in heme acquisition in Gram-positive pathogens. However, how these proteins are involved in heme acquisition is largely unknown.S. pyogenes is capable of utilizing heme derived from human hemoproteins as a source of iron [9, 17]. The heme acquisition machinery in S. pyogenes is believed to consist of Shr, Shp, and HtsABC. Shp and HtsABC are the cell surface heme-binding protein and heme-specific ABC transporter, respectively [4, 12]. Shr, another cell surface protein, is proposed to be a receptor of host hemoproteins [3]; however, its function has not been firmly established. We have been studying the S. pyogenes heme acquisition machinery as a model system for understanding the heme acquisition process in Gram-positive pathogens. Shp rapidly and directly transfers its heme to HtsA, the lipoprotein component of HtsABC, in a concerted two-step process with one kinetic phase [18, 19]. The structure of the Shp heme-binding domain reveals that the Shp heme iron is ligated to Met66 and Met153 [20], and the Met axial ligands are both important for rapid heme transfer from Shp to HtsA [21]. However, the heme source of Shp is not known.

We have proposed that Shp functions to relay heme from host proteins or another

S. pyogenes heme-binding protein to HtsABC [18]. In this study, we found that the rates of ferric heme transfer from oxidized hemoglobin (methemoglobin) to heme-free Shp (apoShp) are similar to those for the dissociation of ferric heme from methemoglobin, suggesting that Shp cannot directly acquire heme from methemoglobin and that Shp may mainly acquire heme from another S. pyogenes protein. We hypothesize that this protein is Shr. To test this hypothesis, recombinant Shr was prepared and characterized. We found that Shr indeed binds heme and, more interestingly, efficiently transfers it to Shp but inefficiently to HtsA. These findings suggest the possibility that Shr is the heme source of Shp and that heme transfer from Shr to Shp is part of the heme acquisition process in S. pyogenes .

Results

Shp appears to indirectly acquire ferric heme from methemoglobin

Heme-binding form of Shp (holoShp) was formed in the incubation of apoShp with human methemoglobin [18]. It was not known whether the formation of holoShp was due to direct heme transfer from methemoglobin or indirect scavenge of ferric heme dissociated from methemoglobin. To examine this issue, the rate for formation of holoShp was compared with that of heme dissociation from methemoglobin. Limited methemoglobin (total 5.8 [mu]M heme) was incubated with 7 to 56 [mu]M apoShp at 25[degrees]C, and the formation of holoShp was monitored by absorbance change at 405 and 425 nm, which present the loss and gain of heme by methemoglobin and apoShp, respectively. The time courses of normalized absorbance change, [DELTA](A

425 -A405 ), fit a two exponential equation (Fig. 1A), but not a single exponential equation (Fig. 1B). Fitting of the data to a two exponential equation resulted in two first-order rate constants. The values of the rate constants did not change significantly with [apoShp] from 7 to 56 [mu]M, giving the mean values [+ -] standard deviation of 0.0065 [+ -] 0.0013 and 0.00041 [+ -] 0.00012 s-1 for the rate constants of the fast and slow phases, respectively. The biphasic kinetics and rate constants are similar to those in the dissociation of heme from methemoglobin using H64Y/V68F apomyoglobin as a heme scavenger [22], in which the fast and slow phases are heme dissociation from the [beta] and [alpha] subunits, respectively [22, 23]. To confirm these similarities, the dissociation of heme from methemoglobin using …

SCHOOL BOARD MEMBER VOLUNTEERS TO OVERSEE PROJECT.(CAPITAL REGION)

Byline: DENNIS YUSKO Staff writer

The Waterford-Halfmoon Union-Free School District will likely approve Thursday a proposal by board member Don Neddo to oversee their $1.9 million building project.

Board President Robert Zordan said Neddo's offer to volunteer as ``clerk of the works'' could save the district as much as $55,000.

``I'm doing it to save the school district money,'' said Neddo. ``I usually work all summer and take the winter off, but this time it will be the other way around. Kind of stupid isn't it?''

Neddo, 66, has worked 44 years as an electrician and was employed as a foreman on several job sites.

A clerk of the …

Peter Gordon takes the reins at John Hancock Financial.(Brief article)

John Hancock Financial Network has named Peter Gordon president, effective Sept. 1.

As president, Gordon is responsible for the overall growth, expansion and profitability of the company. "I'm looking forward to working to bring great products to consumers through a network of knowledgeable agents and advisers. It is an exciting time for John Hancock Financial Network as the organization has begun to expand into new markets and is evolving all of its traditional sales agencies into client-centered marketing luaus. I hope to use my background and prior experience running sales organizations to help accelerate the company's growth" he said in a statement.

Most …

Court reduces sentence for Iraqi shoe thrower

Iraq's highest court on Tuesday reduced the prison sentence for an Iraqi journalist who hurled his shoes at former President George W. Bush from three years to one, a court spokesman said.

Abdul-Sattar Bayrkdar, the spokesman, said the decision was taken because the journalist had no prior criminal history.

The defense appealed the original ruling to the Federal Appeals Court citing an Iraqi law stipulating a maximum sentence of only two years for publicly insulting a visiting foreign leader.

The decision came as Barack Obama made his first official visit to Iraq as U.S. president.

Muntadhar al-Zeidi was sentenced to three years in …

Doggie diet

What's the number one health problem for dogs? You might be surprised to find out that, according to a new study, it's the same runaway health problem affecting an increasing number of people worldwide and especially in the United States: obesity. The second-biggest health danger for dogs is traffic, while disc problems are third.

Almost three-quarters of physiotherapists cited obesity in the survey, which was announced March 6 by the Chartered Society of Physiotherapy, a British medical organization that deals with animal and human health.

But just why are our pets becoming super-sized? For many …

(C) 1999 BI DIRECTORY OF RISK MANAGEMENT CONSULTANTS.(Directory)

CGR

455 W. St. Antoine, Suite 310,

Montreal, Quebec, Canada H22 1J1;

514-392-1253 fax: 514-392-0559

Consulting since: 1987.

1998 revenues

Continuous consulting: 75%

Risk management audits: 14%

Special consulting projects: 10%

Actuarial/accounting services: 1%

Staff

Total: 3

Risk management professionals: 2

Includes: 1 principal consultant, 1 consultant.

Clients

Total: 10

Services: Most risk management services.

Specialties: Manufacturing, technology, global companies.

Compensation: By the project, on retainer, by the hour: $200 per principal consultant, $160 per consultant, $150 per analyst, $45 per clerical.

Officers: Andre Goyette, Jacques Pharand.

Cannon Cochran Management Services Inc.

2 E. Main St.,

Danville, Ill. 61832;

217-446-1089 fax: 217-443-0927

www.ccmsi.com

Consulting since: 1978.

1998 revenues

Total gross revenues: $23,100,000

Consulting revenues: $2,079,000

Continuous consulting: 94%

Risk management audits: 1%

Actuarial/accounting services: 5%

Staff

Total: 301

Risk management professionals: 14

Includes: 14 principal consultants.

Clients

Total: 130

U.S.: 100%

Services: Most risk management services.

Specialties: Provides consulting to all or most types of business or industry.

Compensation: By the project.

Officers: G. Bryan Thomas, president; Rodney Golden, senior vp; Steven Luebbert, vp/chief marketing officer.

Contact: Karen Waclaw, marketing coordinator.

Cantor & Co.

9100 Wilshire Blvd., Suite 445E,

Beverly Hills, Calif. 90212;

310-859-7277 fax: 310-859-7415

www.cantorandco.com

Consulting since: 1982.

1998 revenues

Continuous consulting: 90%

Special consulting projects: 10%

Staff

Total: 6

Includes: 1 principal consultant, 3 analysts.

Clients

Total: 50

U.S.: 95%

Non-U.S. 5%

Services: Alternative risk financing consulting, consulting on design of risk management information systems, loss prevention consulting.

Specialties: Health care providers, transportation, global companies.

Compensation: By the project, on retainer, by the hour: $180 per principal consultant, $120 per analyst, $55 per clerical. …

Ergonomics at work.

Byline: Jim Mackinnon

Aug. 27--Goodyear Tire & Rubber Co.'s top executives were looking for a way to make factories safer and workers more productive.

They weren't satisfied with the records they reviewed, even though the company considered itself an industry leader in safety, said Mike Porter,

Goodyear's director of global health, safety and chemical material management. In addition to serious injuries and lesser cuts and bumps, the data the executives looked over in late 2004 showed factory floor workers with such things as sprains and strains, he said.

"We looked at that and asked, how do we aggressively go after those types of injuries," he said. "And that's how …

суббота, 3 марта 2012 г.

LLOYD VAN FLEET, 85.(CAPITAL REGION)

CHATHAM Lloyd H. Van Fleet, 85, of Chatham, died Sunday in Barnwell Health Facility in Valatie.

Mr. Van Fleet was born in Middletown, Orange County.

He was manager of Middletown Oil Co. He was a golf pro at the Orange County Country Club and sales director and secretary of Columbia Corp. He had also been employed as a sales manager by Continental Can Co. and Fort Orange Paper Co. After his retirement, he had worked part time at Slattery's Store in East Chatham. Many years ago, he operated a newspaper store on Main Street.

Mr. Van Fleet was active in scouting and had served as a finance chairman of Fort Orange Council of Boy …

Paper reveals South Carolina gov's e-mail exchange

Just after South Carolina Gov. Mark Sanford admitted to a yearlong extramarital affair, his state's largest newspaper posted online romantic, suggestive e-mails that it says were exchanged between the chief executive and his Argentinian lover.

The State newspaper of Columbia redacted the full name of the woman, identifying her only as "Maria," but their contents clearly show they were more than friends.

The newspaper says it has had the messages since December, which would be about the time Sanford says his wife found out about the tryst. In a message to The Associated Press, managing editor Steve Brook declined to immediately elaborate on why it …

Howard reportedly talking with Bullets

Free-agent forward Juwan Howard, whose contract with the MiamiHeat was rejected by the NBA, is negotiating with the WashingtonBullets in an attempt to rejoin his former team, the Washington Postreported Sunday.

Citing an unidentified source, the Post also said the NBA likelywill allow the Bullets to exceed the salary cap to re-sign Howard.

Howard became a free agent last month and signed a seven-year,$100.8 million contract with the Heat. But the NBA blocked thecontract last week, saying the Heat exceeded the salary cap byagreeing to pay Howard $9 million this season.

Teams are allowed to exceed the cap to re-sign their own playersbut not to sign players …